An Assembly Automation Approach to Alignment of Noncircular Projections in El…

In single-particle electron microscopy (EM), multiple micrographs of identical macromolecular structures or complexes are taken from various viewing angles to obtain a 3D reconstruction. A high-quality EM reconstruction typically requires several thousand to several million images. Therefore, an automated pipeline for performing computations on many images becomes indispensable. In this paper,…