Identification of biosynthetic intermediates of teaghrelins and teaghrelin-li…

Teaghrelins are unique acylated flavonoid tetraglycosides found in Chin-shin oolong tea,and have been demonstrated to be promising oral ghrelin analogues. The biosynthetic pathway of teaghrelins from quercetin-3-O-rutinoside (rutin) or kaempferol-3-O-rutinoside (nicotiflorin) was proposed to comprise three enzymatic steps according to the identification of putative intermediates in Chin-shin o…