e-journal
The interaction between casein micelles and gold nanoparticles
Abstract.
For the first time, the interaction of casein micelle (CM) with gold nanoparticles (GNPs) was studied
using TEM, UV–visible, FTIR and fluorescence spectroscopy methods. The results show that GNPs bind
to CM surface, leading to the formation of GNP–CM conjugates. GNPs exhibit similar particle diameters,
and the CM structure is retained in GNP–CM conjugates. Furthermore, GNP–CM conjugates display good
stability against salt concentration and pH. The combination of these measurements suggests that GNPs
presumably bind to CM surfaces via complexation with the carboxylate or amine groups on CM surfaces,
but not by electrostatic action.
Keywords:
Protein aggregates
Gold nanoparticles
Interaction
Bioconjugates
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