e-journal
Affecting Cognition and Quality of Life via Aerobic Exercise in Alzheimer’s Disease
Abstract.
Aerobic exercise is a promising behavioral therapy for Alzheimer’s disease
(AD), yet few studies have investigated the effect of aerobic exercise on
cognition in AD. The purpose of this pilot study was to examine the effect
of 6-month aerobic exercise on the change in executive function, global cognition,
quality of life (QOL), and depression in community-dwelling older adults
with mild to moderate AD. A single group, repeated measures design with
outcomes measured at baseline, 3 months, and 6 months was used. Results
show that there were no significant changes in any measures except for
depression (p = .026). There was a trend toward improvement in executive
function and QOL with moderate effect sizes (ESs) and a trend toward deterioration
in global cognition with moderate to large ESs. Randomized controlled
trials are needed to evaluate the therapeutic effect of aerobic exercise
in older adults with AD.
Keywords: exercise, cognition, quality of life, dementia, aging
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