e-journal
Potential Mechanism for the Laser-Fluoride Effect on Enamel Demineralization
Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment
are not well-understood. Using microcomputed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434
(fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive
effect of the laser ( p < 0.001) and fluoride ( p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD)
analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion,
subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated
hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization.
KEY WORDS: low energy, non-invasive, microXRD, micro-CT, caries, mineral loss.
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