e-journal

Sodium fluoride: an ineffective inhibitor of glycolysis

---

Entrenched in current laboratory protocols for the measurement of plasma glucose is the false belief that sodium fluoride (NaF) is an effective inhibitor of glycolysis. The failure of NaF to properly control glycolysis decreases plasma glucose concentrations. The amount of the decrease can be clinically significant. The most recent (2011) laboratory guidelines for diagnosis and management of diabetes mellitus, approved by the American Diabetes Association, no longer recommend
the use of NaF alone to control glycolysis. If plasma cannot be iced and separated from cells within 30 min of collection, the new guidelines recommend the use of a tube that contains a low pH buffer such as citrate. Proper control of glycolysis will affect current glucose cut-off points, but the exact effect is yet to be defined.

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Annals of Clinical Biochemistry

No. Panggil

-

Penerbit

: SAGE Publications Ltd., 2013

Deskripsi Fisik

Annals of Clinical Biochemistry 2013; 50: 3–5

Bahasa

English

ISBN/ISSN

-

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

-

Subjek

BIOKIMIA

Info Detail Spesifik

-

Pernyataan Tanggungjawab

hasnidar/agus

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar