e-journal

Withholding Anticoagulation Following a Single Negative Whole-Leg Ultrasound in Patients at High Pretest Probability for Deep Vein Thrombosis

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Prompt, accurate diagnosis of deep vein thrombosis (DVT) is essential. A single, whole-leg ultrasound (whole-leg US) has been used to exclude DVT, but limited data exist for patients with high pretest probability (PTP) for DVT. This diagnostic management study tested the rate of venous thromboembolism (VTE) in patients with a PTP of ‘‘DVT likely’’ per the simplified Wells score when anticoagulation is withheld based on a single, negative whole-leg US. Consecutive patients presenting during coordinator
shifts with a PTP of DVT likely were enrolled. Anticoagulation was withheld after a single, negative whole-leg US. The outcome was objectively confirmed VTE in 3 months. All 167 patients completed the follow-up. A single patient death was adjudicated as possibly caused by VTE, resulting in a VTE rate of 0.60% (95% confidence interval: 0.02%-3.29%). Whole-leg US should be further studied in diagnostic algorithms that utilize PTP scoring and D-dimer testing.

Keywords venous thromboembolism, ultrasound, management study

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Informasi Detail

Judul Seri

Clinical and Applied Thrombosis/Hemostasis

No. Panggil

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Penerbit

: SAGE Publications Ltd., 2013

Deskripsi Fisik

Clinical and Applied Thrombosis/Hemostasis 19(1) 79-85 ª The Author(s) 2013

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

FARMASI

Info Detail Spesifik

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Pernyataan Tanggungjawab

hasnidar/agus

Versi lain/terkait

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