e-book
Roitt’s essential immunology
As a subject, immunology is exciting and dynamic and to persuade you that it is absolutely worthwhile for you to tackle this new edition we have made very extensive changes to update the previous edition. Accordingly, apart from the introduction of numerous new illustrations, we have:
■ Expanded discussion of pathogen - and danger - associated molecular patterns (PAMPs & DAMPs)
■ Introduced a new section on dendritic cells and their role in antigen processing including cross - presentation
■ Updated sections on B - cell and NK receptors
■ Enhanced discussion of lymphocyte traffi cking
■ Incorporated the latest fi ndings on T - cell subsets, particularly Th 17 and the diversity of regulatory T - cells
■ Recorded newer information on NK and cytotoxic T - cell killing mechanisms
■ Given more insight into the eff ects of aging on immune responses
■ Carried out a major rewrite of the vaccine chapter with new emphasis on mechanisms of action of conventional and carbohydrate vaccines, and new approaches to vaccine development including reverse vaccinology, together with progress in malaria vaccines and adjuvant action
■ Provided new information on novel genetic immunodefi ciency defects, on the origin of AIDS and the ever - expanding plethora of AIDS drugs plus results from the latest HIV vaccine trials
■ Clarifi ed the recent fi ndings on the cellular transformations leading to cancer, the manipulation of the immune system by tumors and the links between infection, infl ammation and cancer
■ Substantially rewritten the chapter on autoimmune diseases.
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