e-journal

Haematological problems in intensive care

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Abstract
Anaemia is common in the ICU patient and is usually due to the interplay between many different factors. Although often this can be safely managed conservatively, red cell transfusion is commonly required. Patients who refuse blood products and patients with critical bleeding pose a particular management challenge. Coagulopathy is also frequently encountered in ICU. It is critical to evaluate the causes and bleeding risk in such patients, as this will determine the subsequent management. In
the stable patient it is often not necessary to correct the coagulopathy. Heparin resistance is failure to reach therapeutic targets using heparin as measured by commonly used laboratory tests. It is influenced by a number of factors relating to the nature of heparin and its mode of action and may result in failure to achieve intended clinical outcomes. Heparininduced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin-dependent antibodies leading to platelet activation
and subsequent thrombocytopenia. Awareness and prompt treatment are essential to prevent morbidity and mortality resulting from the development of thrombosis, which can occur in half of patients with HIT.

Keywords Anaemia; antithrombin; coagulopathy; heparin resistance; heparin-induced thrombocytopenia; massive transfusion

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Ketersediaan

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Informasi Detail

Judul Seri

ANAESTHESIA AND INTENSIVE CARE MEDICINE Volume 16:12 December 2015

No. Panggil

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Penerbit

: Elsevier Ltd., 2015

Deskripsi Fisik

ANAESTHESIA AND INTENSIVE CARE MEDICINE Volume 16:12 December 2015

Bahasa

English

ISBN/ISSN

1472–0299

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

ANASTESI
ANEMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

ETY

Versi lain/terkait

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