e-book
Fundamentals of pharmacology
Fundamentals of Pharmacology is primarily a text for undergraduate and postgraduate students
in the health science disciplines, particularly those in nursing. Students of other health disciplines
whose roles involve pharmacological therapy (such as pharmacy, podiatry, optometry, paramedic
and physiotherapy), as well as those studying basic science, should nd much of the material
relevant to their studies. Qualied health professionals and pharmaceutical company sales
representatives will also nd the information useful in their daily roles. Unashamedly, we have
written a pharmacology textbook for students of the health professions that does not compromise
the scientic basis of the discipline. Many pharmacology texts previously published have been
strong on clinical considerations, yet relatively weak in the science of pharmacology.
Philosophically, our goal is to empower health professionals through an understanding of the
fundamental scientic principles of pharmacology. We believe that, to promote understanding,
the eects of drugs on physiological and pathophysiological processes have to be clearly
explained. We have included a small amount of chemistry and biochemistry where appropriate
in order to facilitate this understanding. With a greater appreciation of the action of drugs and
their target tissues, the reader should be able to deduce what adverse eects to expect, as well as
the precautions and contraindications to consider.
Furthermore, where possible we have tended to describe the important characteristics of
medicine groupings rather than focusing on individual agents, and have used prototypes and
common generics as examples. e rationale for this approach is that new medicines are regularly
entering the market while older agents are removed. e average practitioner cannot possibly
keep up with all these changes. However, if a student knows which grouping a new agent belongs
to, the principal characteristics of the medicine can be easily deduced.
is book is primarily designed to establish the foundations in pharmacology. We encourage
students to refer to the electronic and hard copy references commonly found in the clinical
setting and in hospital wards, such as the Australian Medicines Handbook, MIMS or erapeutic
Guidelines, for more detailed information regarding individual therapeutic agents (e.g. dosage,
special precautions and toxicological information).
We hope that you will nd this textbook a valuable companion in your pursuit of a fundamental
understanding in a most fascinating area of clinical knowledge—pharmacology.
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