e-book

Medicinal Chemistry and Drug Design

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Medicinal chemistry is a discipline at the intersection of chemistry, especially synthetic
organic chemistry, and pharmacology and various other biological specialties, where
they are involved with design, chemical synthesis and development for market of
pharmaceutical agents (drugs). Compounds used in medical applications are most
often organic compounds, which are often divided into the broad classes of small
organic molecules and biologics, the latter of which are most often medicinal
preparations of proteins. Inorganic and organometallic compounds are also useful as
drugs. In the recent years discovery of specific enzyme inhibitors has received great
attention due to their potential to be used in pharmacological applications.

Drug design is the inventive process of finding new medications based on the
knowledge of a biological target. A drug is most commonly an organic small molecule
that activates or inhibits the function of a biomolecule such as a protein, which in turn
results in a therapeutic benefit to the organism. In the most basic sense, drug design
involves the design of small molecules that are complementary in shape and charge to
the biomolecular target with which they interact and therefore will bind to it.
Although extensive research has been performed on medicinal chemistry or drug
design for many years, there is still deep need of understanding the interactions of
drug candidates with biomolecules.

This book titled “Medicinal Chemistry and Drug Design” contains a selection of chapters
focused on the research area of enzyme inhibitors, molecular aspects of drug
metabolism, organic synthesis, prodrug synthesis, in silico studies and chemical
compounds used in relevant approaches. The book provides an overview on basic
issues and some of the recent developments in medicinal science and technology.
Particular emphasis is devoted to both theoretical and experimental aspect of modern
drug design. The primary target audience for the book includes students, researchers,
biologists, chemists, chemical engineers and professionals who are interested in
associated areas.

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Ketersediaan

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Informasi Detail

Judul Seri

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No. Panggil

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Penerbit

Rijeka, Croatia : InTech., 2012

Deskripsi Fisik

vi, 406 Hlm.

Bahasa

English

ISBN/ISSN

978-953-51-0513-8

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA
FARMASI

Info Detail Spesifik

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Pernyataan Tanggungjawab

agus

Versi lain/terkait

Lampiran Berkas

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