e-journal

Successful Treatment of Three Cases of Generalized Pustular PsoriasisWith Granulocyte and Monocyte Adsorption Apheresis

---

Generalized pustular psoriasis (GPP) is a rare form of psoriasis characterized by the presence of variable numbers of sterile pustules appearing in erythematous and scaly lesions, which are associated with moderate to severe constitutional symptoms. It can be life-threatening especially in the elderly; therefore, medical care must be performed in rapid succession of treatment especially in refractory cases. We have performed granulocyte and monocyte adsorption apheresis (GCAP) on three GPP cases associated with several systemic and laboratory findings.

As a result, the edema, erythema and numbers of sterile pustules on the skin lesions were reduced dramatically in all three patients after the first sessions of GCAP therapy. The sizes of the psoriatic lesions were reduced in all three patients following a weekly GCAP treatment for 5 consecutive weeks. Psoriasis area and severity
index on discharge had improved in all three patients. No serious adverse effects were observed for up to at least 8 months after treatment.We therefore considered GCAP as one effective alternative to currently existing therapies, especially for recalcitrant cases of GPP.

Key Words: Generalized pustular psoriasis, Granulocyte and monocyte adsorption apheresis.

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Therapeutic Apheresis and Dialysis

No. Panggil

-

Penerbit

Tokyo : International Society for Apheresis., 2012

Deskripsi Fisik

Therapeutic Apheresis and Dialysis 2012; 16(5):445–448

Bahasa

English

ISBN/ISSN

doi: 10.1111/j.1744-

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

2012; 16(5)

Subjek

KEDOKTERAN

Info Detail Spesifik

-

Pernyataan Tanggungjawab

agus

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar