e-journal
The analysis of multivariate longitudinal data: A review
Longitudinal experiments often involve multiple outcomes measured repeatedly within a set of study
participants. While many questions can be answered by modeling the various outcomes separately, some
questions can only be answered in a joint analysis of all of them. In this article, we will present a review of
the many approaches proposed in the statistical literature. Four main model families will be presented,
discussed and compared. Focus will be on presenting advantages and disadvantages of the different models
rather than on the mathematical or computational details.
Keywords: Mixed models, random effects, shared parameters, marginal models, conditional models, latent variables
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