e-journal

In Vivo Repeatedly Charging Near-Infrared-Emitting Mesoporous SiO 2 /ZnGa 2 O 4 :Cr 3+ Persistent Luminescence Nanocomposites

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Near-infrared (NIR) persistent phosphor ZnGa 2 O 4 :Cr 3+ (ZGC) has unique deep-tissue rechargeable afterglow properties. However, the current synthesis leads to agglomerated products with irregular morphologies and wide size
distributions. Herein, we report on in vivo rechargeable mesoporous SiO 2 /ZnGa 2 O 4 :Cr 3+ (mZGC) afterglow NIR-emitting nanocomposites that are made by a simple, one-step mesoporous template method. At less than 600 °C,
pores in mesoporous silica nanoparticles (MSNs) act as nanoreactors to generate in situ ZnGa 2 O 4 :Cr 3+ NIR-persistent phosphors. The as-synthesized mZGC preserves defi ned size, morphology, and mesoporous nanostructure
of the MSNs. The persistent luminescence of the as-synthesized mZGC is recharged in a simulated deep-tissue environment (e.g., ≈8 mm pork slab) in vitro by using red light (620 nm). Moreover, mZGC can be repeatedly activated in vivo for persistent luminescence imaging in a live mouse model by using white LED as a light source. Our concept of utilizing mesoporous silica as nanoreactor to fabricate ZGC PL nanoparticles with controllable morphology and preserved porous nanostructure paves a new way to the development and the wide application of deep tissue rechargeable ZGC in
photonics and biophotonics.

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Ketersediaan

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Informasi Detail

Judul Seri

Adv. Sci.

No. Panggil

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Penerbit

: The Authors., 2015

Deskripsi Fisik

Adv. Sci. 2015, 2, 1500001

Bahasa

English

ISBN/ISSN

DOI: 10.1002

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

2015, 2,

Subjek

KESEHATAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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