e-journal

Chlorine Dioxide Gas Inactivation of Beta-Lactams

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Allergic reactions to beta-lactams, such as penicillin, can be life-threatening. Due to the large number of
individuals allergic to beta-lactams, a method for their inactivation was explored such that a contaminated
area could be treated and re-used. The goal was to validate a cycle that could be used to treat a pharmaceutical manufacturer’s beta-lactam manufacturing equipment for the future production of non-beta-lactam
compounds. Testing was conducted using chlorine dioxide gas at various concentrations and exposure times
in an effort to achieve the pharmaceutical manufacturer’s required 3-log (99.9%) reduction of eight different
beta-lactams on various surfaces. After a period of cycle development, multiple chlorine dioxide gas cycles at
various concentrations and exposure lengths were shown effective in inactivating the eight beta-lactam compounds to a successful degree.

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Ketersediaan

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Informasi Detail

Judul Seri

Applied Biosafety

No. Panggil

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Penerbit

: ABSA., 2011

Deskripsi Fisik

Applied Biosafety Vol. 16, No. 1, 2011

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

Vol. 16, No. 1, 2011

Subjek

BIOLOGI

Info Detail Spesifik

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Pernyataan Tanggungjawab

agus

Versi lain/terkait

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