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e-journal

Polygenic Influence on Educational Attainment: New Evidence From the National Longitudinal Study of Adolescent to Adult Health

Benjamin W. Domingue [et al.] - Nama Orang;

Recent studies have begun to uncover the genetic architecture of educational attainment. We build on this work using genomewide data from siblings in the National Longitudinal Study of Adolescent to Adult Health (Add Health). We measure the genetic predisposition of siblings to educational attainment using polygenic scores. We then test how polygenic scores are related to social environments and educational outcomes. In Add Health, genetic predisposition to educational attainment is patterned across the social environment. Participants with higher polygenic scores were more likely to grow up in socially advantaged families. Even so, the previously published genetic associations appear to be causal. Among pairs of siblings, the sibling with the higher polygenic score typically went on to complete more years of schooling as compared to their lowerscored
co-sibling. We found subtle differences between sibling fixed-effect estimates of the genetic effect versus those based on unrelated individuals.

Keywords: polygenic score, educational attainment, Add Health, genetic risk score


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Informasi Detail
Judul Seri
AERA Open
No. Panggil
-
Penerbit
New York : SAGE., 2015
Deskripsi Fisik
AERA Open July-September 2015, Vol. 1, No. 3, pp. 1– 13
Bahasa
English
ISBN/ISSN
DOI: 10.1177/2332858
Klasifikasi
-
Tipe Isi
-
Tipe Media
-
Tipe Pembawa
-
Edisi
July-September 2015, Vol. 1, No. 3
Subjek
PENDIDIKAN
Info Detail Spesifik
-
Pernyataan Tanggungjawab
agus
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  • FULL TEXT: Polygenic Influence on Educational Attainment: New Evidence From the National Longitudinal Study of Adolescent to Adult Health
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