e-journal

Murine macrophage inflammatory cytokine production and immune activation in response to Vibrio parahaemolyticus infection

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Vibrio parahaemolyticus is the most common cause of bacterial, seafood‐related illness in the USA.Currently, there is a dearth of published reports regarding immunity to infection with this pathogen.Here, production of both pro‐ and anti‐inflammatory cytokines by V. parahaemolyticus‐infected RAW 264.7 murine macrophages was studied. It was determined that this infection results in increased concentrations of IL‐1a, IL‐6, TNF‐a and IL‐10. Additionally, decreases in cell surface TLR2 and TLR4 and increases in T‐cell co‐stimulatory molecules CD40 and CD86 were discovered. The data presented here begin to identify the immune variables required to eliminate V. parahaemolyticus from infected host
tissues.

Key words cytokine, infection, macrophage, Vibrio parahaemolyticus

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Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Microbiol Immunol

No. Panggil

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Penerbit

: The Societies and Wiley Publishing Asia., 2013

Deskripsi Fisik

Microbiol Immunol 2013; 57: 323–328 doi: 10.1111/1348-0421.12034

Bahasa

English

ISBN/ISSN

doi: 10.1111/1348-04

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

2013; 57

Subjek

KESEHATAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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