e-journal

Toll‐deficient Drosophila is susceptible to Pythium insidiosum infection

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There is a paucity of animal models of pythiosis, a life‐threatening disease of humans and animals, the
immunopathogenesis of which is poorly understood. A pythiosis model was developed by injecting Toll
(Tl)‐deficient Drosophila melanogaster flies with Pythium insidiosum zoospores. The infected Tl mutant
flies had significantly lower survival rates (73.7%) than did control flies. This study reveals the
important role of Tl pathway activation in fly immune response to pythiosis.

Key words mini‐host models, pythiosis, Toll receptors.

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Ketersediaan

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Informasi Detail

Judul Seri

Microbiol Immunol

No. Panggil

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Penerbit

: The Societies and Wiley Publishing Asia., 2013

Deskripsi Fisik

Microbiol Immunol 2013; 57: 732–735 doi: 10.1111/1348-0421.12082

Bahasa

English

ISBN/ISSN

doi: 10.1111/1348-04

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KESEHATAN

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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