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Development of Novel Implantable Intraocular Pressure Sensors to Enhance the Performance in in vivo Tests

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Abstract—In this paper, we proposed a dual-mode intraocular pressure (IOP) sensor that has two separated diaphragms to conduct the changes of inductance and capacitance, and we compared the sensor’s performance with that of the conventional single variable capacitive sensor (single-mode sensor). Both mode sensors were used to monitor the pressure in in vitro tests with multiple media and in in vivo tests with rabbits. First, we demonstrated that the sensitivities of two types of sensors tended
to be different for in vivo and in vitro tests. This was the first known attempt to show changes in the sensitivity and responsivity of IOP sensors in in vivo tests. The sensitivity and phase dip of the dual-mode sensor exceeded that of the single-mode sensor, irrespective of medium due to isolation of capacitive sensor from medium. In this paper, we have provided the equations that were used to evaluate the improvement in sensitivity, and we have shown the coincidence with in vitro and in vivo tests.
Based on the results we achieved, we believe that the dual-mode sensor is more feasible for use as an IOP sensor in in vivo tests, because its responsivity and sensitivity are superior to those of
the conventional sensors.

Index Terms—Glucose, intraocular pressure sensor, implantable, wireless, capacitance, inductance.

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Informasi Detail

Judul Seri

JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, VOL. 24, NO. 6, DECEMBER 2015

No. Panggil

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Penerbit

: IEEE., 2015

Deskripsi Fisik

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Bahasa

English

ISBN/ISSN

1057-7157

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

VOL. 24, NO. 6, DECEMBER 2015

Subjek

MIKROELEKTROMEKANIKAL

Info Detail Spesifik

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Pernyataan Tanggungjawab

ETY

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