e-journal

Rapidly Exploring Random Tree Algorithm-Based Path Planning for Robot-Aided Optical Manipulation of Biological Cells

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In numerous cellular applications, cells are transported to specific positions or extracted from complex cell solutions. Therefore, an efficient cell transportation path planner for these applications is important for avoiding collisions with other cells or obstacles. In this paper, a path planning approach
to transporting cells using a robot-aided optical manipulation system is presented. Optical tweezers functions as a special end-effector in transporting a target cell to the desired position along
the generated path. The path planner is designed based on the rapidly exploring random trees (RRT) algorithm for calculating a collision-free path for cell transportation. Both static and dynamic
path planners are developed. For the dynamic path planner, an online monitoring strategy is employed to dynamically avoid collisions with randomly appeared obstacles caused by environmental influence such as the Brownian movement of microparticles. Experiments of transporting yeast cells are performed to demonstrate the effectiveness of the proposed approach.
Note to Practitioners—Manipulations of cells and other microparticles represent an essential process for most cell-based bioengineering applications, such as cytopathology, cell sociology, and cytotaxonomy. Cell transportation, which is treated as a typical cell manipulation task, has recently received considerable attention because of its wide applications. This paper presents a novel approach to applying RRT-based path planner to cell transportation with a robot-aided optical manipulation system.
The research outcome provides a unique solution to achieving cell transportation automatically and efficiently.
Index Terms—Cell manipulation, optical tweezers, path planning, robotics, RRT, transportation.

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Informasi Detail

Judul Seri

IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING

No. Panggil

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Penerbit

New York : IEEE., 2014

Deskripsi Fisik

IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING, VOL. 11, NO. 3, JULY 2014

Bahasa

English

ISBN/ISSN

1545-5955

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

VOL. 11, NO. 3, JULY 2014

Subjek

TEKNIK

Info Detail Spesifik

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Pernyataan Tanggungjawab

Yuli/Agus

Versi lain/terkait

Lampiran Berkas

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