e-journal

Systematic Approach to Computational Design of Gene Regulatory Networks with Information Processing Capabilities

---

We present several measures that can be used in de novo computational design of biological systems with information processing capabilities. Their main purpose is to objectively evaluate the behavior and identify the biological information processing structures with the best dynamical properties. They can be used to define constraints that allow one to simplify the design of more complex biological systems. These measures can be applied to existent computational design approaches in synthetic biology, i.e.,
rational and automatic design approaches. We demonstrate their use on a) the computational models of several basic information processing structures implemented with gene regulatory networks and b) on a modular design of a synchronous toggle switch.
Index Terms—Computational biology, computational design, gene regulatory networks, information processing, modelling and simulation, modular design, synthetic biology

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS

No. Panggil

-

Penerbit

New York : IEEE., 2014

Deskripsi Fisik

IEEE/ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, VOL. 11, NO. 2, MARCH/APRIL 2014

Bahasa

English

ISBN/ISSN

1545-5963

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

VOL. 11, NO. 2, MARCH/APRIL 2014

Subjek

TEKNIK

Info Detail Spesifik

-

Pernyataan Tanggungjawab

Yuli/Agus

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar