Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning

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Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning

Subham Banerjee [et al.] - Nama Orang;

The current study evaluated the stability potential of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against ()-anatoxin A poisoning. The drug combinations were fabricated in an adhesive matrix system supported by a backing membrane and attached to a temporary release liner. Stability testing of the optimized
formulation was established for 6 months under accelerated study conditions as per International Conference on Harmonisation guidelines. Results obtained after 6 months showed that the optimized patch formulation was stable with respect to drugs content, pH,diffusion, visual inspection, and other analytical parameters.

Keywords:
Eserine International Conference on Harmonisation guidelines Pralidoxime chloride Stability Transdermal patch

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Informasi Detail

Judul Seri: j o u rnal of food and drug a n a l y s i s
No. Panggil: -
Penerbit: : Elsevier Taiwan., 2014
Deskripsi Fisik: j o u rnal of food and drug a n a l y s i s 2 2 ( 2 0 1 4 ) 2 6 4 e2 7 0
Bahasa: English
ISBN/ISSN: -
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: -
Subjek: Food And Health
Info Detail Spesifik: -
Pernyataan Tanggungjawab: Wati/Agus

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FULL TEXT:Accelerated stability testing of a transdermal patch composed of eserine and pralidoxime chloride for prophylaxis against (±)-anatoxin A poisoning

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