e-journal

In vitro antioxidant, antimicrobial and anti-diabetic properties ofpolyphenols of Passiflora ligularis Juss. fruit pulp

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In the present study, anti-radical, anti-diabetic and antimicrobial activities of different solvent extracts of Passiflora ligularis fruits wereinvestigated. Among the various solvents, acetone extract displayed maximum total phenolic (640.70 mg GAE/g extract), tannin (214.30 mgGAE/g extract) and flavonoid contents (387.33 mg RE/g extract). Results of antioxidant studies revealed that the acetone extract of fruits pos-sessed an efficient 2,2-diphenyl-1-picryl-hydrazyl (DPPH•) (IC5019.13 g/mL), 2,2-azinobis (3-ethylbenzothiozoline-6-sulfonic acid) (ABTS•+)(9800.94 mol/L trolox equi/g extract), superoxide (78.27%) and nitric oxide (79.95%) radical scavenging activities, ferric reducing antioxidantpower (43.06 mmol Fe (II)/mg extract), metal chelating (134.53 mg EDTA/g extract) ability. The acetone extract of P. ligularis fruits also exhibitedsignificant (P < 0.005) inhibition activities on α-amylase (82.56%) and α-glucosidase (75.36%) enzymes. Furthermore, the fruits of P. ligularisalso demonstrated antibacterial activities against Gram (+) and Gram (−) bacteria and inhibited the fungal strains Candida albicans (14.85 mm)and Aspergillus niger (13.91 mm) in the disc diffusion method. Quantification of polyphenolics by HPLC showed the presence of ellagic acid,gallic acid, and rutin. Therefore, the results indicate that the fruit pulp of P. ligularis can serve as a potential antioxidative and antimicrobial agentin food and pharmaceutical industries.

Keywords: Passiflora ligularis; Antimicrobial; α-Amylase; α-Glucosidase; Polyphenolics1

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Ketersediaan

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Informasi Detail

Judul Seri

Food Science and Human Wellness

No. Panggil

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Penerbit

: Elsevier B.V., 2014

Deskripsi Fisik

Food Science and Human Wellness 3 (2014) 56–64

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Food And Health

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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