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A Digitally Assisted, Signal Folding Neural Recording Amplifier

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A novel signal folding and reconstruction scheme for neural recording applications that exploits the characteristics of neural signals is described in this paper. The amplified output is ‘folded’ into a predefined range of voltages by using comparison and reset circuits along with the core amplifier. After this output signal is digitized and transmitted, a reconstruction algorithm can be applied in the digital domain to recover the amplified signal from the folded waveform. This scheme enables the use of an analog-to-digital convertor with less number of bits for the same effective dynamic range. It also reduces the transmission data rate of the recording chip. Both of these features allow power and area savings at the system level. Other advantages of the proposed topology are increased reliability due to the removal of pseudo-resistors, lower harmonic distortion and low-voltage operation. An analysis of the reconstruction error introduced by this scheme is presented along with a behavioral model to provide a quick estimate
of the post reconstruction dynamic range. Measurement results fromtwo different core amplifier designs in 65 nmand 180 nm CMOS processes are presented to prove the generality of the proposed scheme in the neural recording applications.Operating from a 1 V power supply, the amplifier in 180 nm CMOS has a gain of
54.2 dB, bandwidth of 5.7 kHz, input referred noise of 3.8 and power dissipation of 2.52 leading to a NEF of 3.1 in spike band. It exhibits a dynamic range of 66 dB and maximum SNDR of 43 dB in LFP band. It also reduces system level power (by reducing the number of bits in the ADC by 2) as well as data rate to 80% of
a conventional design. In vivo measurements validate the ability of this amplifier to simultaneously record spike and LFP signals.
Index Terms—Digitally assisted analog, neural amplifier, neural recording, non-Nyquist reconstruction, signal folding.

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Ketersediaan

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Informasi Detail

Judul Seri

IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS

No. Panggil

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Penerbit

New York : IEEE., 2014

Deskripsi Fisik

IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, VOL. 8, NO. 4, AUGUST 2014

Bahasa

English

ISBN/ISSN

1932-4545

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

VOL. 8, NO. 4, AUGUST 2014

Subjek

TEKNIK

Info Detail Spesifik

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Pernyataan Tanggungjawab

Yuli/Agus

Versi lain/terkait

Lampiran Berkas

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