e-journal
What could probiotic do for us?
Gastrointestinal microbes play important roles in the health and disease of the host. There are many documented evidences which demonstratedthat disturbance of intestinal microbiota is linked to the risk of developing infectious, inflammatory and allergic diseases. Human intestine is homefor a complex consortium of 1013–1014microbial cells. Interactions between the intestinal microbes, pathogens and the host lead to exclusionof toxins (mycotoxins) and pathogens (colonization resistance), interference in disease progression as demonstrated in the prevention of oralinfection, dental caries, diarrhoeas (Antibiotic Associated Diarrhoea, Travellers’ Diarrhoea and Rotavirus Diarrhoea), postoperative infection,respiratory infection and certain cancers. The group of beneficial intestinal microbes termed probiotics alter intestinal epithelial cell tight junctionand immunological functions. Lately, laboratory and clinical studies demonstrated gut-brain axis communication and intestinal microbial (bothpathogens and probiotics) modulation of host psycho-neuroimmunological functions, in relation to depression, anxiety and memory dysfunction.These open up many possibilities of probiotics supplementation for moderating intestinal microbiota as an approach in disease prevention andtreatment.
Tidak ada salinan data
Tidak tersedia versi lain