e-journal

Purification, initial characterization and immune activities ofpolysaccharides from the fungus, Polyporus umbellatus

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2014AbstractPolyporus umbellatus (formerly Grifola umbellatus), an edible fungus, has been used as traditional Chinese medicine. The present investigationaimed to uncover the active ingredients in this fungal species, with the emphasis on its polysaccharides. Two polysaccharides, one from fermentedmycelium and the other from the fruiting body, were chromatographically purified. Molecular weights, anti-microbial and immune activities ofthe polysaccharides were determined. The mycelium polysaccharide was found to have a molecular weight of 857 kDa and consist of glucose andgalactose at a molar ratio of 1.57:1, while the one from the fruiting body, 679 kDa in molecular weight, was also made up of glucose and galactosebut at a molar ratio of 5.42:1. In immune assays, these fungal polysaccharides increased the killing potency of natural killer (NK) and lymphokine-activated killer (LAK) cells from mouse spleen and promoted proliferation of mouse B and T cells. Additionally, both P. umbellatus myceliumand its extract were found to inhibit Escherichia coli and Staphylococcus aureus, but had no effects on Aspergillus niger or Aspergillus nidulans.These results indicated that fermented P. umbellatus mycelium is indeed immune active, most probably due to its ingredients of polysaccharides.The consumption of this fungus may be beneficial for human health.

Keywords: Polyporus umbellatus; Fermented mycelium; Polysaccharide; Immune activities1

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Ketersediaan

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Informasi Detail

Judul Seri

Food Science and Human Wellness

No. Panggil

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Penerbit

: Elsevier B.V.., 2014

Deskripsi Fisik

Food Science and Human Wellness 3 (2014) 73–78

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Food And Health

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

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