e-journal

α-Glucosidase inhibitors isolated from medicinal plants

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Objective: α-Glucosidase inhibitors can be used as a new class of antidiabetic drug. By competitively inhibiting glycosidase activity, theseinhibitors help to prevent the fast breakdown of sugars and thereby control the blood sugar level. This study provides a wealth of informationabout α-glucosidase inhibitors isolated from medicinal plants; this knowledge will be useful in finding more potent antidiabetic candidates fromthe natural resources for the clinical development of antidiabetic therapeutics.Results: 411 compounds exhibiting α-glucosidase inhibitory activity were summarized and isolated them from medicinal plants. The compoundclasses isolated include: terpenes (61) from 14 genus, alkaloids (37) from 11 genus, quinines (49) from 4 genus, flavonoids (103) from 24 genus,phenols (37) from 9 genus, phenylpropanoids (73) from 20 genus, sterides (8) from 5 genus, and other types of compounds (43).Conclusion: Compounds with α-glucosidase inhibitory activity are abundant in nature and can be obtained from several sources. They have highα-glucosidase inhibitory potential, and can be clinically developed for treating diabetes mellitus.

Keywords: α-Glucosidase inhibitor; Inhibitory activity; Medicinal plants

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Ketersediaan

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Informasi Detail

Judul Seri

Food Science and Human Wellness

No. Panggil

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Penerbit

: Elsevier B.V.., 2014

Deskripsi Fisik

Food Science and Human Wellness 3 (2014) 136–174

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Food And Health

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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