e-journal

Metabolic response to 6-week aerobic exercise training and dieting in previously sedentary overweight and obese pre-menopausal women:A randomized trial

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Background: The aim of this study was to compare 6 weeks short-term moderate intensity aerobic exercise and dieting on serum metabolomics and cardio-metabolic risk factors in pre-menopausal women.
Methods: Ninety previously inactive overweight and obese (BMI 25e35 kg/m2) women (age 41.5
7.6 years) were randomized to either a 6-week Nordic walking exercise program (EX, n ¼ 45) or dietary counseling group (DI, n ¼ 45). Body composition, serum glucose, insulin and lipids were measured. Serum low-molecular-weight metabolites and lipid constituents were analyzed by nuclear magnetic resonance spectroscopy. Measurements were done at baseline and 7 days after the last training session.
Results: Six weeks aerobic exercise program yielded reductions in serum free fatty acids (34.7%, 95% confidence interval (CI), 50 to 18,p < 0.001), glucose (9.6%, 95%CI, 15 to 4, p < 0.001) and homeostasis model assessment of insulin resistance (HOMA-IR) (28.7%,95%CI, 48 to 10, p ¼ 0.005) without changes in body weight or fat mass. Diet counseling resulted in loss of body weight (1.5%, 95%CI,2.3 to 0.7, p ¼ 0.001) but no changes in free fatty acids, fasting glucose, or HOMA-IR were found.
Conclusion: Our results indicate that small weight loss does not produce measurable health benefits, whereas short-term regular aerobic exercise can improve glucose and lipid metabolism even in the absence of weight loss in previously sedentary overweight and obese women.
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Keywords: Dieting; Exercise; Metabolism; Metabolomics; Women

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Informasi Detail

Judul Seri

Journal of Sport and Health Science

No. Panggil

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Penerbit

: Shanghai University of Sport., 2014

Deskripsi Fisik

Journal of Sport and Health Science 3 (2014) 217e224

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

Sport And Kesehatan

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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