e-journal
Cardiothoracic Ratio AssociationWith Mortality in Patients on Maintenance Peritoneal Dialysis
The cardiothoracic ratio (CTR) indicates the left ventricular size; however, the significance of the CTR in patients on maintenance peritoneal dialysis (PD) remainds unclear. In this study, 335 PD patients were enrolled and demographic, biochemical, co-morbidity, and dialysisrelated data were obtained. The factors determining CTR were further analyzed.All patients were followed up for two years to investigate the mortality risks. We defined anormal CTR as less than the mean CTR value, mild cardiomegaly as a CTR between the mean and mean + 1 SD, and moderate-to-severe cardiomegaly as more than the mean CTR + 1 SD. Among the 335 patients, 163 patients were lassified as having a normal CTR ( 55.7%). c2-analysis showed that the incidences of malnutrition and anemia were significantly higher in patients with severe cardiomegaly than in patients of the other groups. The CTR was positively correlated with age, but negatively correlated with albumin and hemoglobin levels. Twenty-six patients (7.7%) had died by the end of the study. Cox multivariate analysis revealed that the CTR significantly predicts all-cause two-year mortality in PD patients on maintenance PD; therefore, the CTR correlates with the nutritional and anemic status of PD patients and is a reliable predictor for all-cause two-year mortality. The analytical results of this study support continued efforts to reduce the CTR and treat underlying causes in patients with cardiomegaly.
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