e-journal

Gut pain & visceral hypersensitivity

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Abstract:
Visceral pain is a highly complex entity whose experience is variable in health and disease. It can occur in patients with organic disease and also in those without any readily identifiable structural or biochemical abnormality such as in the functional gastrointestinal disorders (FGID). Despite considerable progress in our understanding of the culpable underlying mechanisms significant knowledge gaps remain, representing a significant unmet need in gastroenterology. A key, but not universal, pathological feature is that patients with FGID often display heightened sensitivity to experimental gut stimulation, termed visceral hypersensitivity. A plethora of factors have been proposed to account for this epiphenomenon including peripheral sensitization, central sensitization, aberrant central processing, genetic, psychological and abnormalities within the stress responsive systems. Further research is needed, bringing together complementary research themes from a diverse array of academic disciplines ranging from gastroenterology to nociceptive physiology to functional neuro-imaging, to address this unmet need.

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Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Pain

No. Panggil

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Penerbit

: SAGE, British Journal of Pain., 2013

Deskripsi Fisik

British Journal of Pain 7(1) 39– 47 © The British Pain Society 2013

Bahasa

English

ISBN/ISSN

DOI: 10.1177/2049463

Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

(2013),7(1)

Subjek

Pain

Info Detail Spesifik

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Pernyataan Tanggungjawab

deliza

Versi lain/terkait

Lampiran Berkas

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