e-journal

Dual use of peptide mass spectra: Protein atlas and genome annotation

---

One of the objectives of genome science is the discovery and accurate annotation of all protein-coding genes. Proteogenomics has emerged as a methodology that provides orthogonal information to traditional forms of evidence used for genome annotation. By this method, peptides that are identified via tandem mass spectrometry are used to refine protein-coding gene models. Namely, these peptides are used to confirm the translation of predicted protein-coding genes, as evidence of novel genes or for correction of current gene models. Proteogenomics requires deep and broad sampling of the proteome in order to generate sufficient numbers of unique peptides. Therefore, we propose that proteogenomic projects are designed so that the generated peptides can also be used to create a comprehensive protein
atlas that quantitatively catalogues protein abundance changes during development and in response to environmental stimulus.

Keywords:
Proteogenomics Proteomics Atlas Annotation

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Current Plant Biology

No. Panggil

-

Penerbit

: Elsevier., 2015

Deskripsi Fisik

Current Plant Biology 2 (2015) 21–24

Bahasa

English

ISBN/ISSN

-

Klasifikasi

NONE

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

2 (2015)

Subjek

KIMIA

Info Detail Spesifik

-

Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar