e-journal

DNase I hypersensitivity mapping, genomic footprinting, andtranscription factor networks in plants

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Understanding gene regulatory networks in plants requires knowledge of cis-regulatory DNA, trans-actingfactors, and their dynamics across development and in response to stimuli. Active cis-regulatory elementsare hypersensitive to cleavage by the endonuclease DNase I. Motifs within DNase I hypersensitive sitesindicate potential trans-acting factor occupancy and, when combined with DNase I cleavage data, canbe used to construct provisional regulatory networks. Several recent studies have applied genome-wideDNase I hypersensitivity mapping to Arabidopsis thaliana and rice, generating chromatin accessibilitylandscapes for an array of tissues, cell types, and treatments. Here, we discuss these studies, with anemphasis on building regulatory networks and possible directions for improvements.

Keywords:DNase I hypersensitivityTranscription factor (TF) networksDHSsGene regulationGenomic FootprintingChromatin accessibilityPlants

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Informasi Detail

Judul Seri

Current Plant Biology

No. Panggil

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Penerbit

: Elsevier., 2015

Deskripsi Fisik

Current Plant Biology 3-4 (2015) 40–47

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

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