Dietary nucleotide supplementation enhances immune responses andsurvival to Streptococcus iniae in hybrid tilapia fed diet containing lowfish meal

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Dietary nucleotide supplementation enhances immune responses andsurvival to Streptococcus iniae in hybrid tilapia fed diet containing lowfish meal

Shi-Yen Shiau [et al.] - Nama Orang;

A feeding trial was conducted to evaluate the effects of nucleotide (NT) supplementation in diet onimmune responses and disease resistance of juvenile hybrid tilapia, Oreochromis niloticus × Oreochromisaureus. Nucleotide was added at 0, 120, 240, 360, 480 and 600 mg NT/kg to low fish meal (6%) and highsoybean meal (56%) basal diet for a total of 6 experimental diets. Each diet was fed to triplicate groups oftilapia (initial body weight 0.15 ± 0.005 g) in a recirculated freshwater rearing system for 10 weeks. Headkidney leukocyte superoxide anion production ratio was higher (P < 0.05) in fish fed diets supplementedwith ≥240 mg NT/kg than that in fish fed the NT unsupplemented control diet. Fish fed the diet supple-mented with 240 mg NT/kg had higher plasma lysozyme activity than fish fed diets supplemented with≤120 mg NT/kg. The stimulation index (SI) of head kidney leukocyte stimulated with ConA was higher infish fed diets supplemented with ≥120 mg NT/kg than that in fish fed the control diet. The SI of leukocytestimulated with PHA-P was higher in fish fed diets supplemented with ≥240 mg NT/kg than in fish feddiets supplemented with ≤120 mg NT/kg. After the feeding trial, 10 fish were randomly selected from eachaquarium and were challenged with Streptococcus iniae for 7 days, higher survival (>80%) were observedin fish fed diets supplemented with NT than fish fed the NT unsupplemented control diet (56.7%). Theseresults suggest that nucleotides supplemented at 120–240 mg NT/kg in diet enhances immune responsesand survival of tilapia fed low fish meal and high soybean meal diet.

Keywords:TilapiaNucleotidesImmune responsesLow fish meal dieta

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Judul Seri: Aquaculture Reports
No. Panggil: -
Penerbit: : Elsevier., 2015
Deskripsi Fisik: Aquaculture Reports 2 (2015) 77–81
Bahasa: English
ISBN/ISSN: -
Klasifikasi: NONE
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: 2 (2015)
Subjek: KIMIA
Info Detail Spesifik: -
Pernyataan Tanggungjawab: Wati/Agus

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FULL TEXT:Dietary nucleotide supplementation enhances immune responses andsurvival to Streptococcus iniae in hybrid tilapia fed diet containing lowfish meal

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