e-journal

A crustin isoform from black tiger shrimp, Penaeus monodon exhibitsbroad spectrum anti-bacterial activity

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Crustaceans have a powerful non-specific immune mechanism that responds to pathogen invasion andtogether with cellular responses, generates powerful humoral factors such as antimicrobial peptides.Crustins are a diverse class of antimicrobial peptides that are expressed by the circulating haemocytesof crustaceans. Several isoforms of this molecule are reported and in this study, one isoform from theblack tiger shrimp, Penaeus monodon was cloned and expressed in Escherichia coli SG 13009. The purifiedrecombinant crustin peptide had a molecular weight of 22 kDa and exhibited potent anti-bacterial activityin vitro against several Gram positive and Gram negative bacteria that included pathogens of aquaticanimals and humans. The recombinant crustin showed a minimal inhibitory concentration of 0.5 g ml−1against the vibrio pathogens of shrimp, which suggests its promise for application in aquaculture.

Keywords:CrustinShrimpPenaeus monodonVibrio harveyiAnti-bacterial activitya

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Ketersediaan

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Informasi Detail

Judul Seri

Aquaculture Reports

No. Panggil

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Penerbit

: Elsevier., 2015

Deskripsi Fisik

Aquaculture Reports 2 (2015) 106–111

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

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Subjek

KIMIA

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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