e-journal

Stripping voltammetric detection of nephrotoxic drug cefitizoxime in wastewater

---

a b s t r a c t:
The objective of the present work is to develop the stripping voltammetric method for determination of nephrotoxic drug cefitizoxime in pharmaceutical formulation and its application to wastewater analysis. Solubilized system of different surfactants viz. cationic, anionic and non-ionic influences the electrochemical response of cefitizoxime. Solubilized system of CTAB containing cefitizoxime enhanced the peak current while anionic and non-ionic showed an opposite effect. The current signal due to the reduction process is a function of concentration of the efitizoxime, pH of medium, type of surfactant and accumulation time at electrode surface. The proposed SWCAdSV (Squarewave Cathodic Adsorptive
Voltammtery) and DPCAdSV (Differential Pulse Cathodic Adsorptive Voltammetry) are linear over concentration range 1.732–6.901 lg/mL and 4.792–30.672 lg/mL with detection limit of 0.76 ng/mL and 2.63 ng/mL, respectively. The method is successfully applied for determination of cefitizoxime in pharmaceutical formulation and wastewater with mean percentage recovery of 99.73% and 98.51%, respectively.

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Analytical Chemistry

No. Panggil

-

Penerbit

Elsevier : ., 2015

Deskripsi Fisik

Analytical Chemistry research 4 (2015), 13-19

Bahasa

English

ISBN/ISSN

Doi: 101016/j.ancr.2

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

(2015), 4

Subjek

ANALISIS KIMIA

Info Detail Spesifik

-

Pernyataan Tanggungjawab

deliza

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar