Angiopoietin Balance in Septic Shock PatientsWith Acute Lung Injury: Effect of Direct HemoperfusionWith Polymyxin B-Immobilized Fiber

Pencarian berdasarkan :

SEMUA Pengarang Subjek ISBN/ISSN Pencarian Spesifik

Pencarian terakhir:

e-journal

Angiopoietin Balance in Septic Shock PatientsWith Acute Lung Injury: Effect of Direct HemoperfusionWith Polymyxin B-Immobilized Fiber

Itaru Ebihara, [et al.] - Nama Orang;

Abstract: Acute lung injury (ALI) in sepsis is characterized by an increase in microvascular permeability, resulting in pulmonary edema. Several studies have suggested that angiopoietin-1 and -2 play a contributory role in the pathogenesis of ALI. Polymyxin B-immobilized fiber column hemoperfusion is effective for sepsis-induced ALI. We investigated the angiopoietin levels before and after direct hemoperfusion with polymyxin B-immobilized fiber column (PMX) therapy. Enzyme-linked immunoassay was used to measure the serum angiopoietin-1 and -2 levels in 25 patients with septic shock treated with PMX. Eleven of the 25 patients were diagnosed with ALI. There was a significant positive correlation between the angiopoietin-1 level and the PaO2/FiO2 ratio, but there was a significant inverse correlation between the angiopoietin-2 level and the PaO2/FiO2 ratio. The mean angiopoietin-1 level before PMX therapy in the ALI group was significantly lower and the mean angiopoietin-2 level was significantly higher than in the non-ALI group.The mean angiopoietin-1 level of the ALI patients in response to PMX therapy was increased during PMX therapy, but that of the non-ALI patients with newly occurring ALI showed a decreased angiopoietin-1 level. On the other hand, the mean angiopoietin-2 level of
the responders was decreased during PMX therapy, but that of patients with newly occurring ALI showed an increased angiopoietin-2 level. This result suggested that each angiopoietin-1 and -2 level may play a role in the pathogenesis ofALI and that PMX therapy ameliorates the angiopoietin balance in patients with ALI in sepsis

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri: Therapeutic Apheresis and Dialysis
No. Panggil: -
Penerbit: : Therapeutic Apheresis and Dialysis © 2011 International Society for Apheresis., 2011
Deskripsi Fisik: Therapeutic Apheresis and Dialysis 15(4):349–354, 2011
Bahasa: English
ISBN/ISSN: doi: 10.1111/j.1744
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: (2011)15(4)
Subjek: TERAPI
APHERESIS DAN DIALYSIS
Info Detail Spesifik: -
Pernyataan Tanggungjawab: deliza

Versi lain/terkait

Tidak tersedia versi lain

Lampiran Berkas

FULLTEXT:Angiopoietin Balance in Septic Shock PatientsWith Acute Lung Injury: Effect of Direct HemoperfusionWith Polymyxin B-Immobilized Fiber

Komentar

Anda harus masuk sebelum memberikan komentar