e-journal

Verification of Inactivation Methods for Removal of Biological Materials from a Biosafety Level 3 Select Agent Facility

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Summary:
The Pitt RBL Management Team has established an internal SOP for inactivation of biological agents for removal to a laboratory operating at a lower biosafety level. All investigators are required to provide a full description of any inactivation procedure, as well as detailed safetytesting
data, for each pathogen. These must be reviewed and approved by the Team prior to routine use. Once the inactivation procedure is approved, the investigator must train his or her personnel to follow only the specified procedure. This allows RBL investigators to perform further analysis of their scientific materials in laboratories outside of the BSL-3 facility. The Team endorses that only inactivation procedures based upon sound science are in use, thatn each laboratorian follows the same written, approved procedure, that validation of the procedure has been performed
and documented, and ultimately that BSL-3 agents including Select Agents are properly inactivated prior to removal from the registered facility. These all provide a level of confidence to both the Team and the RBL investigators that the samples being removed from the RBL BSL-3 facility
are safe for use in laboratories operating at lower biosafety levels. While the SOP described here provides a necessary level of oversight, each individual investigator and trained laboratorian are ultimately responsible for following the approved inactivation procedure to prevent improper support from upper administration levels is critical to ensure compliance with the SOP, as this provides an additional level of oversight on the part of the Team to investigators. This type of support and oversight is necessary to the successful operation of a large, multi-agent BSL-3 facility. Importantly, it also fosters a culture of safety among all researchers

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Ketersediaan

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Informasi Detail

Judul Seri

Applied Biosafety

No. Panggil

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Penerbit

: Applied Biosafety., 2012

Deskripsi Fisik

Applied Biosafety Vol. 17, No. 2, 2012, 70-75

Bahasa

English

ISBN/ISSN

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Klasifikasi

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Tipe Isi

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Tipe Media

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Tipe Pembawa

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Edisi

Vol. 17, No. 2, 2012

Subjek

Biosafety Terapan

Info Detail Spesifik

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Pernyataan Tanggungjawab

deliza

Versi lain/terkait

Lampiran Berkas

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