Impact of NSF/ANSI 49 and Risk Assessment on Exposure Frequency to Formaldehyde during Decontamination of Biological Safety Cabinets at U.S. Naval Medical Research Unit No. 3, Cairo, Egypt

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Impact of NSF/ANSI 49 and Risk Assessment on Exposure Frequency to Formaldehyde during Decontamination of Biological Safety Cabinets at U.S. Naval Medical Research Unit No. 3, Cairo, Egypt

Marian A. Mikhail - Nama Orang; Buhari A. Oyofo - Nama Orang;

Abstract:
Formaldehyde gas, a probable carcinogen, was routinely used for decontamination prior to recertification of Class II Type A2 biological safety cabinets (BSCs) at U.S. Naval Medical Research Unit No. 3 (NAMRU-3) in Cairo, Egypt. During decontamination, the gas is released when paraformaldehyde is heated, causing exposure risks. This article describes methods used to reduce the frequency of potential exposure to formaldehyde of a NAMRU-3 staff member accredited by the National Sanitation Foundation International/American National Standards Institute for Biosafety Cabinetry (NSF/ANSI 49). Risk assessments were performed according to guidelines from the Centers for Disease Control and Prevention,
National Institutes of Health, and Biosafety in Microbiological and Biomedical Laboratories (CDC/NIH BMBL) (U.S. Department of Health and Human Services, 2009). The process was also performed as a mandatory requirement before changing the biological pathogens worked with any given BSC. Of the
NAMRU-3 BSCs that had previously undergone more than 78 paraformaldehyde decontaminations prior to recertification over a 3-year period (2009-2011), 27% required decontamination. This has reduced the use of mandatory formaldehyde gas decontamination prior to any service on a NAMRU-3 BSC by 60%, supporting compliance to the Code of Federal Regulations CFR 1910.1048) (OSHA, 2012) to reduce exposure toformaldehyde.

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Judul Seri: Applied Biosafety
No. Panggil: -
Penerbit: : Applied Biosafety., 2012
Deskripsi Fisik: Applied Biosafety Vol. 17, No. 3, 2012, 142-146
Bahasa: English
ISBN/ISSN: -
Klasifikasi: -
Tipe Isi: -
Tipe Media: -
Tipe Pembawa: -
Edisi: Vol. 17, No. 3, 2012
Subjek: Biosafety Terapan
Info Detail Spesifik: -
Pernyataan Tanggungjawab: deliza

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