e-journal

Factors Affecting Circuit Life During Continuous Renal Replacement Therapy in ChildrenWith Liver Failure

---

Abstract: Despite abnormal clotting, circuits clot during continuous renal replacement therapy (CRRT) in children with acute liver failure (ALF).We report our experience. All children with ALF needing CRRT were studied over 2 years. Patient and circuit factors associated with circuit use were evaluated.Thirty-one children in liver failure (median age 7.4 years) underwent CRRT, of which 17 (54.8%) died. A total of 98 filtration episodes were used. The smallest access catheter was 6.5 Fr, while the largest was 13.5 Fr.The most common filter used was HFO7 (63%). Mean duration (SD) of circuit use was 33.13(30.83) hours. Of the 98 filtration episodes, circuits blocked in 25, whereas the access catheter blocked in 25. Fifty-two circuits were changed electively for a variety of reasons. Prostacyclin was the anticoagulant in 62 filtration episodes.The remaining filtration episodes had either no anticoagulation or heparin.The mean (SD) “downtime” was 5.13 (9.15) hours.We found a significant association between fresh frozen plasma (FFP) use with circuit blockade. Neither the duration of CRRT nor the “downtime” influenced mortality. The CRRT circuits blocked in children despite deranged clotting in liver disease. Circuits are changed for a variety of reasons other than clotting. The use of FFP reduces circuit life.

---

Ketersediaan

Tidak ada salinan data

Informasi Detail

Judul Seri

Therapeutic Apheresis and Dialysis

No. Panggil

-

Penerbit

: Jurnal Therapeutic Apheresis and Dialysis., 2015

Deskripsi Fisik

Therapeutic Apheresis and Dialysis 2015; 19(1):16–22

Bahasa

English

ISBN/ISSN

doi: 10.1111/1744-99

Klasifikasi

-

Tipe Isi

-

Tipe Media

-

Tipe Pembawa

-

Edisi

2015; 19(1):

Subjek

TERAPI APHERESIS AND DIALYSIS

Info Detail Spesifik

-

Pernyataan Tanggungjawab

deliza

Versi lain/terkait

Lampiran Berkas

Komentar

---

Anda harus masuk sebelum memberikan komentar