e-journal

Comparison of ketamine–medetomidine-butorphanol and ketamine–dexmedetomidine-butorphanol anesthesia in rats

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We evaluated the effect of ketamine-dexmedetomidine-butorphanol (K, 80 mg/kg; D, 0.25 mg/kg, B,0.5 mg/kg) and ketaminemedetomidine-butorphanol (K, 80 mg/kg; M, 0.25 mg/kg, B,0.5 mg/kg) administered intraperitoneally, during anesthesia and immediate recovery post surgical phase, in male Wistar Outbreed rats undergoing surgery for free graft sciatic nerve transplantation. Recovery was determined by first reflexes and movements. Results suggest that both anaesthetic protocols were fast and long-acting, providing immobility, loss of consciousness and analgesia. During anesthesia rats subjected to ketamine-dexmedetomidine-butorphanol protocol had lower heart and respiratory
rates compared with the other group (ketamine-medetomidine-butorphanol). During the immediate post surgical phase, rats subjected to ketamine-dexmedetomidine-butorphanol protocol had a slower recovery evolution, associated with higher mortality compared with ketamine-medetomidine-butorphanol.

Keywords: anesthesia, protocols, analgesia, rat

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Ketersediaan

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Informasi Detail

Judul Seri

Agriculture and Agricultural Science Procedia

No. Panggil

-

Penerbit

: Elsevier., 2015

Deskripsi Fisik

Agriculture and Agricultural Science Procedia 6 ( 2015 ) 305 – 308

Bahasa

English

ISBN/ISSN

doi: 10.1016/j.aaspr

Klasifikasi

NONE

Tipe Isi

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Tipe Media

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Tipe Pembawa

-

Edisi

6 ( 2015 )

Subjek

Pertanian

Info Detail Spesifik

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Pernyataan Tanggungjawab

Wati/Agus

Versi lain/terkait

Lampiran Berkas

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