e-journal
The Tactile Sensation Imaging System for Embedded Lesion Characterization
Abstract—Elasticity is an important indicator of tissue health, with increased stiffness pointing to an increased risk of cancer. We investigated a tissue inclusion characterization method for the applicationofearlybreasttumoridentification.Atactilesensation imagingsystem(TSIS)isdevelopedtocaptureimagesoftheembeddedlesionsusingtotalinternalreflectionprinciple.Fromtactileimages,wedevelopedanovelmethodtoestimatethatsize,depth,and elasticity of the embedded lesion using 3-D finite-element-modelbased forward algorithm, and neural-network-based inversion algorithmareemployed.Theproposedcharacterizationmethodwas validatedbytherealistictissuephantomwithinclusionstoemulate the tumors. The experimental results showed that, the proposed characterization method estimated the size, depth, and Young’s modulus of a tissue inclusion with 6.98%, 7.17%, and 5.07% relative errors, respectively. A pilot clinical study was also performed to characterize the lesion of human breast cancer patients using TSIS.
Index Terms—Elasticity imaging, mechanical imaging, optical imaging, tactile imaging system, tactile sensor, tumor detection.
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