Abstract Severe sepsis is a heterogenous condition affecting multiple organ systems, and is commonly encountered in the hospital setting due to both community and nosocomial infections. Although the incidence of severe sepsis has increased over the past decades, there is evidence that mortality in developed world settings has improved. Management of the septic patient involves rapid evaluation…
Abstract The immediate response to infection involves the innate immune system, which consists of many cell types and factors. The cells of the innate immune system include the different types of white blood cells and tissue residing cells such as macrophages and mast cells. This immediate response to infection involves an inflammatory response which locally causes vasodilation and increased v…