This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state varia…
Sample preparation is a pivotal part of the integral LC‐MS bioanalysis, which has been heavily employed in the determination of drugs, drug metabolites, biomarkers, and other molecules of interest in various biological matrices (e.g. fluids or tissues) for decades. It has been playing an important role in a variety of human healthcare studies, ranging from drug discovery and development, th…
A sound knowledge of the biomolecular structure aided by appropriate bioanalytical techniques is indispensable to elucidate the mechanism of action of biological macromolecules and their function at large. The present book intends to provide a good introduction and understanding on a range of biomolecular and bioanalytical cum biophysical techniques and is primarily aimed at the advanced unde…
The book starts with an overview of the single molecule/particle catalysis by introducing concisely the history of some typical study methods for single molecule/particle nanocatalysis (Chapter 1), showing the origins of all kinds of techniques for the detection of some weak signals. Then, there are individual discussions based on different detection tools. Firstly, the physical/mathematical b…
In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last deca…