Ditapis dengan
The guardians of inherited oncogenic vulnerabilities
Similar to seemingly maladaptive genes in general, the persistence of inherited cancer-causing mutant alleles in populations remains a challenging question for evolutionary biologists. In addition to traditional explanations such as senescence or antagonistic pleiotropy, here we put forward a new hypothesis to explain the retention of oncogenic mutations. We propose that although natural defens…
- Edisi
- -
- ISBN/ISSN
- doi:10.1111/evo.1280
- Deskripsi Fisik
- Evolution 70-1: 1–6
- Judul Seri
- Evolution
- No. Panggil
- -
Evolutionary perspective of cancer: myth, metaphors, and reality
The evolutionary perspective of cancer (which origins and dynamics result from evolutionary processes) has gained significant international recognition over the past decade and generated a wave of enthusiasm among researchers. In this context,several authors proposed that insights into evolutionary and adaptation dynamics of cancers can be gained by studying the evolutionary strategies of organ…
- Edisi
- -
- ISBN/ISSN
- doi:10.1111/eva.1226
- Deskripsi Fisik
- Evolutionary Applications 8 (2015) 541–544
- Judul Seri
- Evolutionary Applications
- No. Panggil
- -
The guardians of inherited oncogenic vulnerabilities
Similar to seemingly maladaptive genes in general, the persistence of inherited cancer-causing mutant alleles in populations remains a challenging question for evolutionary biologists. In addition to traditional explanations such as senescence or antagonistic pleiotropy, here we put forward a new hypothesis to explain the retention of oncogenic mutations. We propose that although natural defens…
- Edisi
- 70-1
- ISBN/ISSN
- doi:10.1111/evo.1280
- Deskripsi Fisik
- Evolution 70-1: 1–6
- Judul Seri
- Evolution
- No. Panggil
- -
Evolutionary perspective of cancer: myth, metaphors, and reality
The evolutionary perspective of cancer (which origins and dynamics result from evolutionary processes) has gained significant international recognition over the past decade and generated a wave of enthusiasm among researchers. In this context, several authors proposed that insights into evolutionary and adaptation dynamics of cancers can be gained by studying the evolutionary strategies of orga…
- Edisi
- 8 (2015)
- ISBN/ISSN
- 1752-4571
- Deskripsi Fisik
- Evolutionary Applications; 8 (2015) 541–544
- Judul Seri
- Evolutionary Applications
- No. Panggil
- -
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