Quercetin (Q), a bioflavonoid ubiquitously distributed in vegetables, fruits, leaves, and grains, can be absorbed, transported, and excreted after oral intake. However, little is known about Q uptake and metabolism by macrophages. To clarify the puzzle, Q at its noncytotoxic concentration (44mM) was incubated without or with mouse peritoneal macrophages for different time periods. Medium alone…
This study isolated polysaccharides from strawberry (SP) and mulberry (MP) fruit juice to compare their cytokine secretion regulatory and antiapoptotic activities using murine primary splenocytes. SP and MP in the absence or presence of lipopolysaccharide (LPS) were administered to splenocytes for 48 hours. The culture supernatant was used for cytokine secretion assay using the enzyme-linked im…