Abstract: Despite abnormal clotting, circuits clot during continuous renal replacement therapy (CRRT) in children with acute liver failure (ALF).We report our experience. All children with ALF needing CRRT were studied over 2 years. Patient and circuit factors associated with circuit use were evaluated.Thirty-one children in liver failure (median age 7.4 years) underwent CRRT, of which 17 (54.8…