Abstract: This review describes the susceptibilities of all currently HHS-listed and HHS/USDA Overlap select agents and toxins to 8 chemical and 2 physical decontaminants: alcohols, aldehydes, bleach/hypochlorite, iodine, peroxides, phenolics, quaternary ammonium compounds, strong base, dry heat, and steam autoclaving. Inactivation protocols from the literature are presented to facilitate de…