Mixture design analysis of solvent extractor effects on epicatechin, epigallo…

a b s t r a c t: This paper reports an RP-HPLC-UV-DAD study of the effects of four solvents and their mixtures on the extraction and antioxidant activities of three main catechins, epicatechin (EC), epigallocatechin gallate (EGCG) and epigallocatechin (EGC) of Camellia sinensis L. leaves for two harvests. The extraction efficiency solvent was measured by the chromatographic peak areas. The re…