Binding interactions of niclosamide with serum proteins

A study of the binding of niclosamide (NC) to serum proteins such as human serum albumin, hemoglobin, and globulin was carried out using fluorescence and UV-visible spectroscopy. Interactions between NC and these proteins were estimated by Stern eVolmer and van’t Hoff equations. The binding constants and the thermodynamic parameters, DH, DS, and DG at different temperatures were also determin…