κ-Carrageenan was explored to improve genistein solubility by matrix retention. The corresponding maximum value in the efficiency of retention (Re) (50.48 mg/100 mg) was achieved when variables were set as: pH 4.76, temperature 52.12 ◦C and genistein concentration 0.27 mg/mL. The coefficient of determination (R2) of the response surface regression model presented in this study was 0.9848. Th…